CTNNB1 anticorps

N° du produit ABIN6296226

Cet anticorps anti-CTNNB1 est un anticorps Souris Monoclonal détectant CTNNB1 dans WB et IF. Adapté pour Humain, Chien, Poulet et Boeuf (Vache).

Aperçu rapide pour CTNNB1 anticorps (ABIN6296226)

Antigène: CTNNB1 (Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1))

Reactivité: Humain, Chien, Poulet, Boeuf (Vache)

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CTNNB1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-CTNNB1 anticorps

Fonction: Mouse anti-Human/Cow/Dog/Chicken Beta Catenin Antibody [Sodium Azide Free]

Specificité: Cell surface, cytoplasmic, cell junctions

Purification: Chicken b-Catenin was used as the immunogen for the b-Catenin antibody.

Immunogène: Chicken b-Catenin was used as the immunogen for the b-Catenin antibody.

Information d'application

Indications d'application: Immunofluorescence: 1-2 μg/mL
WB: 1-2 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: In 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Détails sur CTNNB1

Antigène: CTNNB1 (Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1))

Autre désignation: Catenin beta-1

Sujet:

Target Description: The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. [RefSeq]

Gene Symbol: CTNNB1///CTNNB///OK///SW-cl.35///PRO2286

ID gène: 1499

UniProt: P35222

Pathways: Signalisation WNT, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Tube Formation, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2